| Contents Notes |
"Children have been identified as a subpopulation of concern for the evaluation of potential risks from chemicals. Tiered approaches to exposure assessments have been often used in regulatory assessment of different populations' exposures to chemicals. The goal of the tiered approach for exposure assessment is to begin with less complex, default-driven, screening methods and to proceed, when necessary, to mover complex, data-driven, chemical- and scenario-specific methods that reduce the uncertainty in estimates of exposure. Currently there are a wide number of software packages available, or under development, that can assist in various tiers of a children's exposure assessment. This paper begins with a brief review of the critical issues in the evaluation of children's exposures to chemicals (Section 2.0). The paper then presents a review of the exposure software (Section 3.0) an evaluates their potential for use at various points in a tiered evaluation (Section 4.0)."--Introduction. |
