Record Display for the EPA National Library Catalog
RECORD NUMBER: 7 OF 20Main Title | Fish Model as an Indicator for Teratogenic Substances. | |||||||||||
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Author | Middaugh, D. P. ; Hemmer, M. J. ; | |||||||||||
CORP Author | Environmental Research Lab., Gulf Breeze, FL. Office of Research and Development. | |||||||||||
Publisher | 1994 | |||||||||||
Year Published | 1994 | |||||||||||
Report Number | EPA/600/A-94/202; | |||||||||||
Stock Number | PB95-122966 | |||||||||||
Additional Subjects | Marine fishes ; Teratogens ; Models ; Toxicity ; In vivo analysis ; Embryos ; Silversides ; Statistical analysis ; Test methods ; Acute exposure ; Marine biology ; Biological effects ; Biological indicators ; Reprints ; Menidia beryllina | |||||||||||
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Collation | 8p | |||||||||||
Abstract | A fish model, suitable for use as an indicator for teratogenic substances, is described. Individual blastula stage embryos of the inland silverside, Menidia beryllina, are exposed to teratogens in sealed tissue culture tubes containing 6 ml of saline test media, 5(0/00) salinity and 25 + or - 1C. Individual embryos are examined daily and tetra enumerated using a system that ranks craniofacial (CR), cardiovascular (CV) and skeletal (SK) responses. Procedures for statistical analysis of data are described. |