Record Display for the EPA National Library Catalog

RECORD NUMBER: 14 OF 15

OLS Field Name OLS Field Data
Main Title Silicone A-187 Seven-Day Rabbit Skin Inunction during Seventeen Calendar Days with Cover Letter.
CORP Author Union Carbide Corp., Danbury, CT.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Publisher 5 May 1975
Year Published 1975
Report Number 878211971;
Stock Number OTS-0206065
Additional Subjects Toxicity ; Rabbits ; Laboratory animals ; Organo-silane ester ; Dosage ; Mortality ; Body weight ; Liver weight ; Kidney weight ; Silicone A-187 ; Skin inunction
Holdings
Library Call Number Additional Info Location Last
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Status
NTIS  OTS-0206065 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 09/29/2008
Collation 148p
Abstract
A group of four male albino rabbits received 7 inunctions of Silicone A-187 over a period of 17 calendar days. The dosage level was 1.0 ml/kg. A shared control group was inuncted with 2.0 ml/kg of distilled water and served as the control for dosages of both 1 and 2 ml/kg. The dosed group was statistically equivalent to the control group in all criteria of stress examined, namely: mortality, body weight change, liver and kidney weight per se and as percentage of body weight. Therefore, the no ill-effect level for a 7-day inunction of Silicone A-187 on rabbits is greater than 1.0 ml/kg/inunction.