Record Display for the EPA National Library Catalog

RECORD NUMBER: 309 OF 2132

OLS Field Name OLS Field Data
Main Title Causes of papillomas on fish exposed to chlorinated sewage effluent /
Author Grizzle, John M. ; Melius, P.
Other Authors
Author Title of a Work
Melius, Paul.
CORP Author Auburn Univ., AL.;Environmental Research Lab., Gulf Breeze, FL.
Publisher U.S. Environmental Protection Agency, Environmental Research Laboratory,
Year Published 1984
Report Number EPA/600/3-84/076; EPA-R-809336
Stock Number PB84-223023
Subjects Mutagenicity testing. ; Fish populations--Alabama. ; Fishes--Effect of water pollution on. ; Sewage--Purification--Chlorination. ; Sewage--Chlorination
Additional Subjects Papilloma virus ; Fishes ; Chlorination ; Sewage treatment ; Toxicity ; Exposure ; Carcinogens ; Organic compounds ; Mutagens ; Neoplasms ; Ictalurus melas
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB84-223023 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 01/01/1988
Collation 32 pages ; 28 cm
Abstract
This research was initiated to determine the cause of oral papillomas in black bullheads (Ictalurus melas) from the final oxidation pond of the Tuskegee, Alabama, sewage treatment plant. The water in this pond was chlorinated effluent from the sewage treatment plant. The presence of a carcinogenic and mutagenic chemical in the effluent of a sewage treatment plant was indicated by papillomas developing on caged black bullheads, glucuronosyltransferase induction in caged channel catfish, and Ames-test mutagenicity of water extract. Unlike previously studied fish papillomas, virus-like particles were not present in the tumor cells. Although mutagenic and carcinogenic chemicals have not been identified in the wastewater, chlorine is implicated as a factor contributing to the induction of the papillomas because the prevalence of papillomas on wild black bullheads exposed to the effluent decreased from 73% to 23% after the chlorination rate was reduced.
Notes
"PB84-223023." "July 1984." Includes bibliographical references. Microfiche.