Record Display for the EPA National Library Catalog

RECORD NUMBER: 14 OF 22

OLS Field Name OLS Field Data
Main Title Physiological Methods for Assessment of Timethyltin Exposure.
Author Dyer, Robert S. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1982
Report Number EPA-600/J-82-323;
Stock Number PB83-223610
Additional Subjects Toxicology ; Assessments ; Senses ; Pathology ; Exposure ; Reprints ; Tin/trimethyl ; Limbic system ; Neurotoxicity
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB83-223610 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 8p
Abstract
Trimethyltin has been reported to produce morphological alterations in the brain which are primarily restricted to the limbic system. A variety of physiological measures of limbic system integrity are discussed in terms of their ability to detect TMT-induced dysfunction. In addition, several measures of sensory system dysfunction are discussed. It is concluded that limbic system dysfunction induced by this compound is detected more efficiently by intrahippocampal evoked potentials than by more gross measures of dysfunction. It is also concluded that relying upon preliminary descriptions of pathological alterations to direct physiological studies may provide an incomplete description of neurotoxicity.