Record Display for the EPA National Library Catalog

RECORD NUMBER: 4 OF 25

OLS Field Name OLS Field Data
Main Title Detection of Chemically Induced Aneuploidy in 'Saccharomyces cerevisiae': An Assessment of Mitotic and Meiotic Systems.
Author Resnick, M. A. ; Mayer, V. W. ; Zimmermann, F. K. ;
CORP Author Oak Ridge National Lab., TN. ;National Inst. of Environmental Health Sciences, Research Triangle Park, NC. ;Food and Drug Administration, Washington, DC. Genetic Toxicology Branch. ;Technische Hochschule Darmstadt (Germany, F.R.). Inst. fuer Mikrobiologie.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.
Year Published 1986
Report Number EPA-68-02-3839; EPA/600/J-86/077;
Stock Number PB86-205572
Additional Subjects Toxicology ; Bacteria ; Reprints ; Aneuploidy ; Mutagenesis ; Saccharomyces cerevisiae
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB86-205572 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/21/1988
Collation 16p
Abstract
A committee of scientists was established by the U.S. Environmental Protection Agency to appraise the current state of aneuploidy test methodology, to compile and analyze published data on the chemical induction of aneuploidy, and to provide guidance for additional test development and validation. The committee was organized into 9 working groups, representing different eukaryotic organisms ranging from fungi to whole mammals. The Environmental Mutagen, Carcinogen, and Teratogen Information Program at Oak Ridge National Laboratory identified and provided literature to the working groups. The 9 reports were prepared by the individual working groups. The reports include: (1) descriptions of the available testing approaches and general principles to be followed for protocol development, (2) criteria for evaluating data, and (3) recommendations for future test development and basic research. The evaluated results are presented in tables.