Main Title |
Synthetic studies towards bioactive heterocycles : Pyrrole-2-carbaldehydes and N-Heterocyclic amino acids / |
Author |
Wood, James,
|
Year Published |
2018 |
OCLC Number |
1066227278 |
Subjects |
Heterocyclic compounds--Synthesis ;
Bioactive compounds--Synthesis ;
Amino acids--Synthesis ;
Pyrroles--Synthesis
|
Internet Access |
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
ELBM |
QD341.E7W66 2018 |
|
AWBERC Library/Cincinnati,OH |
02/26/2020 |
|
Collation |
xii, 437 pages : illustrations (some colour) ; 30 cm |
Notes |
"A thesis submitted in fulfilment of the requirements for the degree of Doctor of Philosophy, School of Chemical Sciences, University of Auckland, March 2018." Includes bibliographical references. |
Contents Notes |
This thesis is comprised of two parts and describes synthetic efforts towards bioactive N-heterocyclic scaffolds. Part One describes synthetic studies towards pyrrole-2-carbaldehydes using a Maillard-type reaction ... Part Two describes synthetic studies towards N-heterocyclic amino acid isosteres of L-alloenduracididine (430) ; a component of the recently isolated antibiotic teixobactin (423) which exhibits potent bactericidal activity without detectable antimicrobial resistance. |