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RECORD NUMBER: 261 OF 2643

OLS Field Name OLS Field Data
Main Title Carbon Monoxide Exposure and Human Visual Detection Thresholds.
Author Hudnell, H. K. ; Benignus, V. A. ;
CORP Author North Carolina Univ. at Chapel Hill. Dept. of Psychology.;Health Effects Research Lab., Research Triangle Park, NC. Neurotoxicology Div.
Publisher c1989
Year Published 1989
Report Number EPA-68-02-3800; EPA/600/J-89/219;
Stock Number PB90-146119
Additional Subjects Visual perception ; Carbon monoxide ; Thresholds(Perception) ; Toxicity ; Graphs(Charts) ; Dark adaption ; Test methods ; Sensitivity ; Motion ; Exposure ; Humans ; Reprints ; Carboxyhemoglobin ; Dose-response relationships
Holdings
Library Call Number Additional Info Location Last
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Status
NTIS  PB90-146119 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/15/1990
Collation 11p
Abstract
In order to test for low level CO exposure effects on vision, a battery of visual tests was administered to male college students. All subjects completed the battery of tests both before and during an exposure period in a double-blind study. Experimental subjects received CO during the exposure period, whereas control subjects received only room air. The battery of visual tests was designed for the assessment of scotopic (dark adapted, rod mediated) vision, photopic (light adapted, cone mediated) vision, the pattern detection process and the motion detection process. Contrast thresholds for the detection of stimulus pattern and for the detection of stimulus motion were measured under both photopic and scotopic viewing conditions, and sensitivity was monitored throughout the course of dark adaptation by measuring luminance thresholds. The results indicated that visual function in healthy, young adult males was not affected by a COHb level of about 17% which was maintained for over 2 hours.