||Use of Primate Folliculogenesis Models in Understanding Human Reproductive Biology and Applicability to Toxicology.
Sakai, C. N. ;
Hodgen, G. D. ;
||Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment. ;Jones Inst. for Reproductive Medicine, Norfolk, VA. Dept. of Obstetrics and Gynecology.
Reproductive system ;
Animal models ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
The nonhuman primate reproductive system provides an excellent model for studying basic physiological processes applicable to humans. The article reviews hormonal observations and experimental manipulations useful in the evaluation of ovarian events in various stages of the reproductive life. As the need arises, primate reproductive toxicological studies may clarify questions relevant to human risk evaluations. Evaluation of reproductive toxicological observations may reveal biological parameters defining premature reproductive failure. (Copyright (c) 1988 Pergamon Press plc.)