||Studies of Reproductive Cyclicity: Evaluation of Computer Modeling as a Tool.
Ferin, M. ;
Bogumil, R. J. ;
||Columbia Univ., New York. Coll. of Physicians and Surgeons.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.
||EPA/600/J-88/291 ; OHEA-R-252
Reproductive system ;
Computerized simulation ;
Menstrual cycle ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
Assessment of toxic effects on human reproductive function using fetal health or teratogenic criteria presumes the conditions of parental fertility. Toxins that compromise fecundity through derangement of the menstrual cycle may require quite different models and criteria. Nonlinear dynamic interactions of the hormonal and morphological components of the menstrual cycle add to the difficulty of such studies. With appropriate mathematical models, computer simulation can provide a useful guide to the design and conduct of in vivo experiment. (Copyright (c) 1988 Pergamon Press plc.)