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RECORD NUMBER: 41 OF 50

OLS Field Name OLS Field Data
Main Title Studies of Reproductive Cyclicity: Evaluation of Computer Modeling as a Tool.
Author Ferin, M. ; Bogumil, R. J. ;
CORP Author Columbia Univ., New York. Coll. of Physicians and Surgeons.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.
Publisher c1988
Year Published 1988
Report Number EPA/600/J-88/291 ; OHEA-R-252
Stock Number PB89-202261
Additional Subjects Reproduction(Biology) ; Toxicity ; Humans ; Reproductive system ; Computerized simulation ; Endocrinology ; Models ; Fecundity ; Embryos ; Reprints ; Menstrual cycle ; Risk assessment
Holdings
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Status
NTIS  PB89-202261 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 12/18/1989
Collation 9p
Abstract
Assessment of toxic effects on human reproductive function using fetal health or teratogenic criteria presumes the conditions of parental fertility. Toxins that compromise fecundity through derangement of the menstrual cycle may require quite different models and criteria. Nonlinear dynamic interactions of the hormonal and morphological components of the menstrual cycle add to the difficulty of such studies. With appropriate mathematical models, computer simulation can provide a useful guide to the design and conduct of in vivo experiment. (Copyright (c) 1988 Pergamon Press plc.)