Main Title |
Approach to Environmental Risk Assessment Using Avian Toxicity Tests (Journal Version). |
Author |
Shirazi, M. A. ;
Bennett, R. S. ;
Lowrie, L. ;
|
CORP Author |
Corvallis Environmental Research Lab., OR. ;Northrop Services, Inc., Corvallis, OR. |
Publisher |
c1988 |
Year Published |
1988 |
Report Number |
EPA/600/J-88/258; |
Stock Number |
PB89-143747 |
Additional Subjects |
Lethal dosage ;
Hazardous materials ;
Weibull density functions ;
Toxicity ;
Birds ;
Bioassay ;
Tables(Data) ;
Pesticides ;
Statistical distributions ;
Mathematical models ;
Reprints ;
Risk assessment ;
Environmental tests ;
Dose-response relationships
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB89-143747 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
11p |
Abstract |
Toxicity tests results are often condensed into a single endpoint (LC50) to facilitate their use in environmental management. The single number cannot distinguish between two tests with equal LC50s but dissimilar slopes at LC50 and it cannot describe the response at low and high dose levels. Some chemicals produce a flat response at low dose levels, others produce a steep response. The management of different chemicals requires different strategies and a more comprehensive approach to analysis of test data than use of a single endpoint. An alternative analysis of test data using Weibull survivor function produces information on the overall form of the dose-response curve and enables calculation of toxicity, the slope, and errors at arbitrary protection levels, including the conventional 50% level. (Copyright (c) 1988 Springer-Verlag New York Inc.) |