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RECORD NUMBER: 477 OF 590Main Title | Six-month Chronic Toxicity Study of Kf-96 (Polydimethylsiloxane) in Rats with Cover Letter dated 04/08/94. | |||||||||||
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CORP Author | Safety Res inst Chem Compounds; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. | |||||||||||
Year Published | 1994 | |||||||||||
Report Number | 86940001752 | |||||||||||
Stock Number | OTS0572799 | |||||||||||
Additional Subjects | Toxicology ; Health effects ; Polydimethylsiloxane ; Subchronic Toxicity ; Mammals ; Rats ; Oral ; Gavage ; Toxic substances ; Laboratory animals ; CAS No 63148-62-9 | |||||||||||
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Collation | 55p | |||||||||||
Abstract | The following dosages were used for both males and females for a duration of 14 weeks: 0.3, 1.0, 3.0, 10.0 ml/kg. It was concluded that KF-96 (100cs) elicits no changes suggestive of disorders when administered orally to rats at 10 ml / kg/ day or lower dosage levels for 6 consecutive months. |