Record Display for the EPA National Library Catalog
RECORD NUMBER: 1220 OF 3839Main Title | Initial Submission: Acute Inhalation Toxicity of Carbon Oxide Sulfide in Rats with Cover Letter dated 08/10/1992. | |||||||||||
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CORP Author | Du Pont de Nemours (E.I.) and Co., Newark, DE. Haskell Lab. for Toxicology and Industrial Medicine.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. | |||||||||||
Year Published | 1992 | |||||||||||
Report Number | 8EHQ-0992-10971 | |||||||||||
Stock Number | OTS0571009 | |||||||||||
Additional Subjects | Toxicology ; Health effects ; Toxic substances ; Carbon oxide sulfide ; Acute toxicity ; Mammals ; Rats ; Inhalation ; CAS No 463-58-1 | |||||||||||
Holdings |
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Collation | 16p | |||||||||||
Abstract | The purpose of this study was to determine the inhalation LC50 for carbonyl sulfide in male Cr1:CD(reg) rats. Groups of 10 male Crl:CD(reg) rats, 7-8 weeks old and weighing 238 to 275 8, were exposed to atmospheres containing carbonyl sulfide for single 4-hr. periods. Prior to and post-exposure, rata were housed in suspended stainless steel, uire-mesh cages. Purina certified Rodent Chows No. 5002 and water were supplied ad libitum. During exposure, all rats were observed and clinical signs note . Following exposure, rats were weighed and observed daily (excluding weekends) for a 14-day recovery period. |