The mission of the United States Environmental Protection Agency (EPA) is to protect public health and safeguard and improve the natural environmentthe air, water, and land upon which life depends. Achievement of this mission requires the application of sound science to the assessment of environmental problems and to the evaluation of possible solutions. The National Center for Environmental Research (NCER) at EPA is committed to providing the best products in high-priority areas of scientific research through significant support for long-term research. The Office of Research and Developments (ORD) Environmental Monitoring and Assessment Program (EMAP) identifies integrating information across multiple scales as one of its largest challenges. This approach is based on The Committee on Environment and Natural Resources (CENR) publication entitled Integrating the Nations Environmental Monitoring and Research Networks and Programs, A Proposed Framework. In support of this identified research need, NCER issued a Request for Applications (RFA) on Regional Scale Analysis and Assessment in 1997. It was followed up with subsequent RFAs in 1998 and 1999. The purpose of these solicitations was to support research that would lead to the development and demonstration of approaches to link sitespecific information with regional survey data and remote sensing imagery for conducting regional-level ecological assessments. A total of 11 grants have been funded under this program. This research represents part of the extramural component of ORDs Environmental Monitoring and Assessment Program (EMAP).

Cover title. "September 2000." Includes bibliographical references and index. "EPA/600/R-00/059."

Introduction -- Assessment of forest disturbance in the mid-Atlantic region : a multiscale linkage between terrestrial and aquatic ecosystems / Keith N. Eshleman ... [et al.] -- Multilevel statistical modeling for generalizing from case studies / Richard A Berk .. [et al.] -- Regional scale impacts of Phase I of the Clean Air Act amendments : the relation between emmissions and concentrations, both wet and dry / Gene E. Likens, Tom Butler -- Regional analysis of variation in Adirondack Lake ecosystems : landscape scale determinants of dissolved organic compound / Michael L. Pace, Charles D Canham, Michael Papaik -- Methodologies for extrapolating from local to regional ecosystem scales : scaling functions and thresholds in animal response to landscape pattern and land use / John A. Wiens, Beatrice Van Horne -- Application of remotely sensed data to regional analysis and assessment of stream temperature in the Pacific northwest / Stephen Burges -- Effects of N deposition gaseous N loss from temperate forest ecosystems / Peter M. Groffman ... [et al.] -- Regional analysis of net ecosystem productivity of Pacific northwest forests : scaling methods, validation, and results across major forest types and age classes / Beverly E. Law .. [et al.] -- Multiscale effects of forest fragmentation and landscape context on population health of birds / Thomas E. Martin [et al.] -- Regional ecological assessment of the Rio Grande riparian corridor : a multidisciplinary approach to understanding anthropogenic effects on riparian communities in semi-arid environments / Jay Raney ... [et al.] -- A hierarchical patch dynamics approach to regional modeling and scaling / Jianguo Wu.