||Distribution of Relative Error of Toxicity of Herbicides and Metals to 'Arabidopsis'.
Shirazi, M. A. ;
Ratsch, H. C. ;
Peniston., B. E. ;
||Corvallis Environmental Research Lab., OR. ;ManTech Environmental Technology, Inc., Corvallis, OR.
Test methods ;
Laboratory animals ;
Arabidopsis thaliana ;
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The authors conducted toxicity tests with a group of chemicals that produce a wide range of response in Arabidopsis. They analyzed and integrated the test results in a form that is suitable for use in environmental research and management. Our emphasis was to broaden the utilization of test results from the traditional focus upon a single test, a single chemical, and a single EC50 endpoint to a class of similar tests of different chemicals and the utilization of a whole dose-response surface for endpoints. The test data were used in this paper as an example for demonstrating the stated emphasis. Toxicity tests with plants often produce stimulatory response at low dose levels and contain variabilities due to natural differences in the population of test organisms. The dose-response curve from these tests cannot be reduced using conventional probit analysis.