Main Title |
Inhibition of the sodium-iodide symporter by perchlorate : an evaluation of life stage sensitivity using physiologically based pharmacokinetic (PBPK) modeling. |
Publisher |
U.S. Environmental Protection Agency, Office of Research and Development, |
Year Published |
2009 |
Report Number |
EPA/600/R-08/106A |
OCLC Number |
750259758 |
Subjects |
Perchlorates--Health aspects--Research ;
Sodium iodide
|
Internet Access |
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
EJBD POD |
Internet only |
|
Headquarters Library/Washington,DC |
09/12/2011 |
|
Collation |
1 online resource (ix, 78 pages) : digital, PDF file, illustrations, charts |
Notes |
Title from title screen (viewed on Sept. 7, 2011). "May 2009". "EPA/600/R-08/106A". Includes bibliographical references (p. 42-44). |
Contents Notes |
"This report provides an analysis of perchlorate-mediated inhibition of the sodium-iodide symporter (NIS) in humans using published PBPK models, focusing on the degree of NIS inhibition as a function of lifestage. The models provide information that may be used to address differences in human responses to perchlorate across lifestages." |