Record Display for the EPA National Library Catalog

RECORD NUMBER: 337 OF 1617

OLS Field Name OLS Field Data
Main Title Drinking Water Criteria Document for Glyphosate.
CORP Author Dynamac Corp., Rockville, MD.;Environmental Protection Agency, Washington, DC. Office of Drinking Water.
Publisher Apr 90
Year Published 1990
Stock Number PB90-215369
Additional Subjects Potable water ; Toxicology ; Water quality ; Herbicides ; Mutagens ; Carcinogens ; Reproduction(Biology) ; Lethal dosage ; Exposure ; Laboratory animals ; Mitochondria ; Glyphosate ; Pharmacokinetics ; Water pollution effects(Humans) ; Water pollution effects(Animals) ; Health hazards ; Carcinogenicity tests ; Path of pollutants ; Mutagenicity tests
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB90-215369 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 08/27/1990
Collation 57p
Abstract
Glyphosate is the common name for N-(phosphonomethyl)glycine. No published reports were found on the toxicokinetics of glyphosate. Other available data, although inadequate, indicated that glyphosate is rapidly absorbed by test animals, and that over 90% is excreted within 48 hours. Very few data on the health effects of glyphosate in mammals were found in the open literature, and most information on the toxicity of this compound has been provided by the Monsanto Company. Oral LD50 values have been reported in two different studies to be 4,873 and 5,600 mg/kg in rats. The oral LD50 has been reported to be 1,568 mg/kg in mice. The dermal LD50 in rabbits was estimated to be more than 5,000 mg/kg. Hyperemia of the lungs has been reported to be the most prominent effect following glyphosate poisoning, with severe stress, accelerated breathing, elevated temperature, occasional convulsive movements, and rigor preceding death.