Record Display for the EPA National Library Catalog

RECORD NUMBER: 313 OF 1617

OLS Field Name OLS Field Data
Main Title Drinking Water Criteria Document for Antimony.
CORP Author Dynamac Corp., Rockville, MD.;Environmental Protection Agency, Washington, DC. Office of Drinking Water.
Publisher Apr 90
Year Published 1990
Stock Number PB90-215435
Additional Subjects Potable water ; Toxicology ; Water quality ; Antimony ; Mutagens ; Carcinogens ; Reproduction(Biology) ; Lethal dosage ; Exposure ; Laboratory animals ; Body weight ; Enzymes ; Enzyme inhibitors ; Dose-response relationships ; Pharmacokinetics ; Water pollution effects(Humans) ; Water pollution effects(Animals) ; Health hazards ; Carcinogenicity tests ; Path of pollutants ; Mutagenicity tests ; Enzyme activation
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB90-215435 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 08/27/1990
Collation 98p
Abstract
Antimony (Sb) is a semimetal element of Group V, sharing some chemical properties with lead, arsenic, and bismuth. The most stable valence states of antimony are Sb(3+) and Sb(5+). Numerous inorganic and organic compounds of antimony are known. Most of the common antimony compounds are slightly to readily soluble in water. Antimony is thought to exert its toxic effects by interacting with intracellular enzymes or cofactors. A number of sulfhydryl-containing compounds reduce the toxic effects of antimony, suggesting that it may bind to cellular sulfhydryl groups. Antimony has been reported to increase the activity of heme oxygenase, to increase the action of thyroid hormone, and to decrease the toxicity of selenium, but the mechanisms of these effects are not known. Antimony has been found to be mutagenic in several test systems, and various types of tumors, including lung neoplasms, have been induced in rats upon inhalation exposure; however, no evidence has been found that orally ingested antimony is carcinogenic.