Record Display for the EPA National Library Catalog
RECORD NUMBER: 50 OF 175
|OLS Field Name||OLS Field Data|
|Main Title||Effect of Organic Phosphorus Compounds and Alkylating Agents on the Rat Fetus.|
|Author||Kimbrough, Renate D. ; Gaines., Thomas B. ;|
|CORP Author||National Communicable Disease Center, Atlanta, Ga.|
|Report Number||found in PB-280 889|
|Stock Number||PB-280 901, found in PB-280 889|
|Additional Subjects||Pesticides ; Toxicology ; Malathion ; Diazinon ; Phosphorus organic compounds ; Rats ; Physiological effects ; Laboratory animals ; Experimental data ; Parenteral infusions ; Lethal dosage ; Mutations ; Dosage ; Tables(Data) ; Toxicity ; Bioassay ; Reprints ; Fetuses ; Toxic substances ; Teratogenesis ; Parathion ; DDVP insecticide ; Tepa ; Apholate|
The effects of parathion, dichlorvos, diazinon, malathion, apholate, and tepa on the rat fetus were studied when the material was given intraperitoneally. At levels producing toxic symptoms in the dams, parathion, dichlorvos, diazinon, apholate, and tepa were found to affect the fetus either by causing malformations, resorptions, or reducing the weight of the fetus and placenta. Malathion at toxic dosage levels neither affected the weight of the fetus nor produced malformations. At dosage levels which were tolerated by the dams, parathion, diazinon, and tepa caused a great number of resorptions. The incidence of resorptions was not higher than that of the controls in rats that had been given dichlorvos, malathion, or apholate.
contained in PB-280 889 titled Journal Articles on Toxicology. Group 14.