Record Display for the EPA National Library Catalog

RECORD NUMBER: 86 OF 2622

OLS Field Name OLS Field Data
Main Title Acute Effects of 0.2 ppm Ozone in Patients with Chronic Obstructive Pulmonary Disease.
Author Solic, John J. ; Hazucha, Milan J. ; Bromberg, Philip A. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1982
Report Number EPA-600/J-81-330;
Stock Number PB83-129981
Additional Subjects Respiratory diseases ; Toxicology ; Ozone ; Patients ; Epidemiology ; Sensitivity ; Smoking ; Reprints ; Chronic obstructive lung disease ; Air pollution effects(Humans)
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB83-129981 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 9p
Abstract
Epidemiologic data suggest that patients with chronic obstructive pulmonary disease (COPD) might be more sensitive than normal persons to the respiratory effects of oxidant pollutant exposure. The study was designed to determine the response of patients with COPD to ozone. Thirteen white men with nonreversible airways obstruction of whom 8 were current smokers, were randomly exposed for 2 h to air and to 0.2 ppm ozone on 2 consecutive days using a single-blind crossover design. During either exposure, subjects exercised for 7.5 min every 30 min. Measures of respiratory mechanics obtained pre-exposure and postexposure were not significantly affected by either exposure.