Record Display for the EPA National Library Catalog

RECORD NUMBER: 2 OF 4

OLS Field Name OLS Field Data
Main Title Gene Expression in Pre-Implantation Mammalian Embryos.
Author Schultz, G. A. ; Heyner, S. ;
CORP Author Calgary Univ. Health Sciences Centre (Alberta). Dept. of Medical Biochemistry. ;Pennsylvania Univ. Medical Center, Philadelphia. Dept. of Obstetrics and Gynecology.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.;National Institutes of Health, Bethesda, MD.
Publisher c1992
Year Published 1992
Report Number NIH-HD23511; EPA/600/J-93/171 ; OHEA-R-474
Stock Number PB93-194397
Additional Subjects Embryos ; Preimplantation phase ; Gene expression ; Mothers ; Oogenesis ; Genetic transcription ; Cell membrane ; Biological transport ; Blastocyst ; Species diversity ; Growth substances ; Reprints ; Female genetic risk ; Genomic imprinting
Holdings
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Status
NTIS  PB93-194397 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 08/23/1993
Collation 17p
Abstract
The pre-implantation mammalian embryo is initially under the control of maternal informational macromolecules that are accumulated during oogenesis. Subsequently, the genetic program of development becomes dependent upon new transcription derived from activation of the embryonic genome. Several embryonic transcripts including those that encode growth factors, cell junction components and plasma membrane ion transporters are required for normal progression of the embryo to the blastocyst stage. The pattern of genes expressed and the overall program of development is subject to the influences of genomic imprinting as well as external influences encountered by the embryo within the maternal reproductive tract. (Copyright (c) 1992 Elsevier Science Publishers B.V.)