Record Display for the EPA National Library Catalog
RECORD NUMBER: 27 OF 80
|OLS Field Name||OLS Field Data|
|Main Title||Evaluation of the potential carcinogenicity of N-Nitrosomethylvinylamine (4549-40-0) /|
|CORP Author||Syracuse Research Corp., NY. ;Environmental Monitoring and Services, Inc., Washington, DC.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.|
|Publisher||U.S. Environmental Protection Agency, Office of Emergency and Remedial Response ;|
|Report Number||EPA-68-03-3112; EPA-68-03-3182; EPA/600/8-91/166; OHEA-C-073-154|
|Additional Subjects||Nitroso compounds ; Nitrosamines ; Toxicity ; Risk assessment ; Public health ; Exposure ; Hazardous materials ; Neoplasms ; Tolerances(Physiology) ; Carcinogenicity ; Dose-response relationships ; CAS: 4549-40-0|
|Collation||22 pages ; 28 cm|
N-Nitrosomethylvinylamine is a probable human carcinogen, classified as weight-of-evidence Group B2 under the EPA Guidelines for Carcinogen Risk Assessment. Bioassays have sufficiently demonstrated the animal carcinogenicity although no control data for animal studies exist for N-nitrosomethylvinylamine. Therefore, evidence on potential carcinogenicity from animal studies is 'Sufficient', and the evidence from human studies is 'No Data'. Data available are inadequate for calculating a potency factor and no quantitative inferences can be made. N-Nitrosomethylvinylamine is, therefore, assigned to the median potency factor range and placed in potency group 2 under the CAG's methodology for evaluating potential carcinogens. Combining the weight-of-evidence group and potency group, N-nitrosomethylvinylamine is assigned a 'MEDIUM' hazard ranking.
Cover title. "June 1988." Includes bibliographical references. Microfiche.