Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Contribution to the Problem of the Origin of Nitrosamines After Inhalation of Nitrogen Oxides (K Otazce Vzniku Nitrosaminu po Vdechovani Kyslicniku Dusiku).
Author Kaut., V. ;
CORP Author Environmental Protection Agency, Research Triangle Park, N.C. Translation Services Section.
Year Published 1970
Report Number EPA-TR-76-569;
Stock Number PB-258 787-T
Additional Subjects Nitrogen oxides ; Nitroso compounds ; Amines ; Respiration ; Nitroso compounds ; Rats ; Laboratory animals ; Exposure ; In vitro analysis ; Lung ; Tissues(Biology) ; In vivo analysis ; Translations ; Czechoslovakia ; Pathology ; Cigarette smoking ; Air pollution effects(Animals) ; Nitrosamines
Library Call Number Additional Info Location Last
NTIS  PB-258 787-T Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/23/1988
Collation 7p
The carcinogenic effect of nitroso compounds, and of nitrosamines in particular, is well-known. The possibility that these compounds form as a result of the action of nitrogen oxides on lung tissue has been assumed on the grounds that nitrosamines in tobacco smoke develop as a result of the reaction between NO2 and amino compounds, and that the amino groups of pulmonary proteins, or their decomposition products, therefore could be also nitrosylated. Serfontein (1966), Neurath (1967) and Tomatis (1967) found traces of nitrosamines in tobacco smoke, but not in lung tissue. The report is concerned with the problem of the effect of nitrogen oxides on the organism, and also looks into the possibility of the origin of nitroso compounds and nitrosamines in the exposed lungs of animals.