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RECORD NUMBER: 17 OF 17

OLS Field Name OLS Field Data
Main Title Pulmonary Dosimetry of Nitrogen Dioxide in Animals and Man.
Author Miller, E. J. ; Graham, J. A. ; Overton, J. H. ; Myers, E. T. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1983
Report Number EPA-600/D-83-091;
Stock Number PB83-243394
Additional Subjects Nitrogen dioxide ; Toxicology ; Respiratory system ; Mathematical models ; Air pollution ; Laboratory animals ; Humans ; Rabbits ; Guinea pigs ; Rats ; Chemical reactions ; Lungs ; Comparison ; Public health ; Air pollution effects(Humans) ; Air pollution effects(Animals)
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB83-243394 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/23/1988
Collation 15p
Abstract
Using a general mathematical model formulation for the tranpsort of gases in the lungs, the authors studied the regional pulmonary deposition of nitrogen dioxide (NO2) in man, rabbits, guinea pigs, and rats, The model formulation utilizes lung morphometric data and includes parameters reflecting physiochemical properties of NO2, ventilatory patterns, and chemical ractions of NO2 with components of the protective layer linings of the lungs. Sensitivity of model predicted doses to changes in some of the above parameters are discussed as well as qualitative comparisons between animals and man in the shape of the dose curves.