Record Display for the EPA National Library Catalog

RECORD NUMBER: 36 OF 53

OLS Field Name OLS Field Data
Main Title Neurobehavioral Methods Used in Neurotoxicological Research.
Author Tilson, H. A. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. Neurotoxicology Div.
Publisher 1993
Year Published 1993
Report Number EPA/600/J-94/033;
Stock Number PB94-137213
Additional Subjects Nervous system ; Behavioral symptoms ; Toxicology ; Toxicity ; Dose-response relationships ; Neurotoxins ; Environmental pollutants ; Motor activity ; Sensory thresholds ; Risk assessment ; Reprints ; Neurotoxicology ; Tier testing ; Cognitive functions ; Sensory functions
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB94-137213 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 05/14/1994
Collation 10p
Abstract
Behavioral endpoints are being used with greater frequency in the hazard identification phase of neurotoxicology risk assessment. One reason behavioral procedures are used in animal neurotoxicology studies is that they evaluate neurobiological functions known to be affected in humans exposed to neurotoxic agents, including alterations in senory, motor, autonomic and cognitive function. In hazard identification, behavioral tests are used in a tier-testing context. Tests in the first tier are designed to determine the presence of neurotoxicity. Second tier tests are used to characterize neurotoxicant-induced effects on sensory, motor and cognitive function.