Record Display for the EPA National Library Catalog
RECORD NUMBER: 19 OF 53
|OLS Field Name||OLS Field Data|
|Main Title||Guidelines for neurotoxicity risk assessment.|
|CORP Author||Environmental Protection Agency, Washington, DC. National Center for Environmental Assessment.|
|Publisher||Risk Assessment Forum, U.S. Environmental Protection Agency ; National Technical Information Service, distributor,|
|Report Number||EPA/630/R-95/001 F|
|Subjects||Neurotoxicology--United States. ; Risk assessment.|
|Additional Subjects||Environmental pollutants ; Risk assessment ; Nervous system disorders ; Guidelines ; Neurotoxins ; Toxicity ; Health hazards ; Contaminats ; Exposure ; Vulnerability ; Children ; Infants ; Public health ; Dose-response relationships ; Methodology ; Procedures ; Neutrotoxicity|
|Collation||viii, 77 p. ; 28 cm.|
The Guidelines set forth principles and procedures to guide EPA scientists in evaluating environmental contaminants that may pose neurotoxic risks, and inform Agency decision makers and the public about these procedures. Developed by a cross-Agency Technical Panel organized by the Risk Assessment Forum, these Guidelines are the Agency's first statement on setting principles and procedures to guide EPA scientists in conducting neurotoxicity risk assessments. A link between human exposure to some chemical substances and neurotoxicity has been firmly established. The Guidelines emphasize that risk assessment will be conducted on a case-by-case basis. They stress that information will be fully presented in Agency risk assessment documents and that Agency scientists will identify the strengths and weaknesses of each assessment by describing uncertainties, assumptions, and limitations, as well as the scientific basis and rationale for each assessment. The Guidelines bridge gaps in risk assessment methodology and data by identifying these gaps and the importance of the missing information to the risk assessment process, encouraging research and analysis that will lead to new risk assessment methods and data. The Guidelines specifically note the special vulnerability of the nervous system of infants and children to environmentally relevant chemicals and provide guidance for the interpretation of data from developmental and reproductive studies involving assessment of nervous system structure and function.
"Published on May 14, 1998, Federal Register 63(93):26926-26954." "April 1998." "EPA/630/R-95/001F." Includes bibliographical references (p. 66-73). Shipping list no.: 1999-0031-P.