Record Display for the EPA National Library Catalog

RECORD NUMBER: 9 OF 30

OLS Field Name OLS Field Data
Main Title Effects of manganese and their modification by hexametaphosphate /
Author Bull, Richard J.
CORP Author Health Effects Research Lab., Cincinnati, Ohio. Water Quality Div.
Publisher Health Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency,
Year Published 1977
Report Number EPA/600/1-77/024
Stock Number PB-272 264
OCLC Number 53324845
Subjects Manganese. ; Trace elements in animal nutrition.
Additional Subjects Manganese ; Toxicity ; Dopamine ; Ingestion(Biology) ; Dosage ; Rats ; Laboratory animals ; Experimental data ; Potable water ; Water supply ; Recommendations ; Toxicology ; Water treatment ; Physiological effects ; Exposure ; Nervous system disorders ; Tables(Data) ; Standards ; Inorganic phosphates ; Environmental health ; Water pollution effects(Humans) ; Maximum permissible exposure level ; Threshold limit values ; Occupational safety and health ; Toxic tolerances ; Metaphosphoric acid
Internet Access
Description Access URL
http://nepis.epa.gov/Exe/ZyPDF.cgi?Dockey=9101OMN2.PDF
Holdings
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Status
NTIS  PB-272 264 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 01/01/1988
Collation 20 pages ; 28 cm.
Abstract
The ability of oral Mn(+2) to produce the depletions of dopamine in the corpus striata characteristic of the Parkinson-like syndrome in manganese workers was examined in rats. A second objective of this work was to study the biological interactions between Mn(+2) and sodium hexametaphosphate ((NaPO3)6) administered simultaneously in drinking water. The authors conclude that Mn(+2) in drinking water presents little hazard in terms of central nervous system involvement in a homogeneous population. The involvement of genetic factors which have been suggested to account for the sporadic occurrence of Parkinson-like symptoms in Mn(+2) workers can not be excluded. The use of (NaPO3)6 for Mn(+2) complexation as an alternative to removal in drinking water treatment appears safe from a health standpoint if carefully controlled to avoid excessive amounts of (NaPO3)6.
Notes
"May 1977." Microfiche.