||Adenocarcinoma of the Retinal Pigment Epithelium in the Guppy 'Poecilia reticulata' Peters.
Fournie, J. W. ;
Hawkins, W. E. ;
Walker, W. W. ;
||Environmental Research Lab., Gulf Breeze, FL. ;Gulf Coast Research Lab., Ocean Springs, MS.
Pigment epithelium of eye ;
Eye neoplasms ;
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A single case of adenocarcinoma of the retinal pigment epithelium occurred in a guppy, Poecilia reticulata, Peters. This is the first such tumour reported from fishes. The left eye of the affected fish was severely exophthalmic because of a large intraocular tumour mass. The tumour, which displaced normal retina anteriorly, consisted mainly of melanin-containing epithelial cells. Neoplastic cells were bilayered and arranged in a tubular pattern. The tumour was confined to the orbit. Although the specimen was from a group exposed to a mixture of halogenated organic compounds, the lesion was not considered to have been chemically induced because of its rare occurrence within the group as a whole. (Copyright (c) 1992 Academic Press Limited.)