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RECORD NUMBER: 303 OF 1145

OLS Field Name OLS Field Data
Main Title Cumulative Exposure to Arsenic and Its Relationship to Respiratory Cancer among Copper Smelter Employees.
Author Lee-Feldstein, A. ;
CORP Author Michigan Univ., Ann Arbor. School of Public Health.;Environmental Protection Agency, Washington, DC. Carcinogen Assessment Group.
Year Published 1986
Report Number EPA-68-03-3108; EPA/600/J-86/403;
Stock Number PB88-104203
Additional Subjects Arsenic ; Malignant neoplasms ; Industrial medicine ; Copper industry ; Respiratory system ; Carcinogens ; Smelting ; Reprints ; Cancer
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB88-104203 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/21/1988
Collation 9p
Abstract
To explore the role of arsenic as a human carcinogen, the respiratory cancer mortality experience (1938 to 1977) of 8,045 white male smelter employees in Montana was examined relative to cumulative exposure to arsenic trioxide and was compared with that of the white male population of the same region. Exposure to arsenic was estimated for various work areas from industrial hygiene reports of average concentrations present in the smelter. Respiratory cancer mortality was analyzed further by time period of first employment and maximum lifetime exposure to arsenic trioxide. When exposure was estimated with arithmetic means of measured concentrations among men first employed prior to 1925, respiratory cancer mortality increased linearly with increasing cumulative exposure group, ranging from two to nine times expected; among those first employed in the period 1925 to 1947 it also increased linearly with increasing cumulative exposure group.