||Chemical Characterization of Mutagenic Fractions of Particles from Indoor Coal Combustion: A Study of Lung Cancer in Xuan Wei, China.
Chuang, J. C. ;
Wise, S. A. ;
Cao, S. ;
Mumford, J. L. ;
||Health Effects Research Lab., Research Triangle Park, NC. ;Battelle, Columbus, OH. Atmospheric Science and Applied Technology. ;National Inst. of Standards and Technology (CSTL), Gaithersburg, MD. Organic Analytical Research Div. ;Institute of Environmental Health and Engineering, Beijing (China).
Indoor air pollution ;
Air pollution effects(Humans) ;
Chemical analysis ;
Lung neoplasms ;
Combustion products ;
Polycyclic aromatic hydrocarbons ;
Xuan Wei(China) ;
Coal burning ;
Semivolatile organic compounds
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
In the rural Xuan Wei County, Yunnan Province, lung cancer mortality rates for women are among the highest in China. Most of these women are nonsmokers, and studies have shown that lung cancer in Xuan Wei is associated with domestic use of smoky coal under unvented conditions. The objective of the study is to determine the chemical constituents that may be linked to the high lung cancer rates in Xuan Wei using the bioassay-directed fractionation method. The results indicated that the presence of three to four-ring alkylated PAHs in the sample extract is a significant factor that may be linked to the high incidence of lung cancer in Xuan Wei, China. (Copyright (c) 1992 The American Chemical Society).