Record Display for the EPA National Library Catalog

RECORD NUMBER: 7 OF 8

OLS Field Name OLS Field Data
Main Title Theoretical foundations of cancer chemotherapy introduced by computer models
Author Jackson, Robert C.
Publisher Academic Press,
Year Published 1992
OCLC Number 25592026
ISBN 0123790301
Subjects Cancer--Chemotherapy--Computer simulation ; Pharmacokinetics--Computer simulation ; Cancer cells--Computer simulation ; Antineoplastic Agents--pharmacokinetics ; Computer Simulation ; Models, Chemical ; Neoplasms--drug therapy
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
EJBM  RC271.C5J33 1992 Headquarters Library/Washington,DC 11/21/1997
Collation xiv, 447 p. : ill. ; 24 cm. + 1 computer disk (5 1/4 in.)
Notes
System requirements for computer disk: IBM PC or compatible; IBM-BASIC, BASICA, or Microsoft GWBASIC (need Microsoft Quick Basic 4.5 to compile source codes). Includes bibliographical references (p. 427-435) and index.
Contents Notes
Introduction: models as tools for teaching and research -- Cell cycle effects of drugs -- Anticancer drug selectivity -- Quiescent cells, differentiated cells, and lost cells -- Pharmacokinetic models -- Invasion and metastasis -- Blood-brain barrier -- Cancer treatment and the immune response -- Drug resistance and its implications for treatment strategy -- Growth kinetics of large tumors -- Biochemical basis of anticancer drug selectivity -- Biochemical principles of drug interaction -- Cytokinetics, pharmacokinetics, and inhibition kinetics: a unified model.