||Ames Salmonella/mammalian Microsome Mutagenicity Test and Reverse Mutation Assay - E. Coli Wp2 Uvra a (Standard Plate Test and Preincubation Test) (Oct. 19, 1988) W-letter 12/16/1991.
||BASF A.G., Limburgerhof (Germany, F.R.). Agricultural Research Station.; BASF Corp., Mount Olive, NJ.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Health effects ;
4-methylbenzaldehyde (104-87-0) ;
Gene Mutations ;
In Vitro ;
Toxic substances ;
Laboratory animals ;
CAS No 104-87-0
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
P-Tolualdehyde (CAS No. 104-87-0) was evaluated for mutagenicity in the Ames test (strains TA1535, TA100, TA1537, TA98) with and without metabolic activation (S-9 mix) and in the Escherichia coli (WP2 uvrA) reverse mutation assay at a dose range of 20 ug - 5000 ug/plate in the standard plate test (SPT) and 4 ug - 2500 ug/plate in the preincubation test (PIT). No bacteriotoxic effect was observed with E. coli. Bacteriotoxicity was detected in all Salmonella strains detected at 2500 ug/plate (PIT) and at 5000 ug/plate (SPT). The test substance was determined to be non- mutagenetic.