Record Display for the EPA National Library Catalog

RECORD NUMBER: 38 OF 287

OLS Field Name OLS Field Data
Main Title CHO/HGPRT Test using Gulfcrown Grease E.P. No. 2.
CORP Author Gulf Oil Corp., Pittsburgh, PA., Medical and Health Resources Division.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Publisher 1 Sep 1983
Year Published 1983
Report Number OTS-878213847;
Stock Number OTS-0206330
Additional Subjects CHO cells ; Mutations ; Cell cultures ; Paraffin ; Toxicity ; Mammals ; Laboratory animals ; Chemical analysis ; Toxic substances ; Enzymes ; Microsomes ; Mutagenic pathways ; China hamster ovary(CHO) ; Gulfcrown grease ; Chlorinated paraffin ; HGPRT test
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Status
NTIS  OTS-0206330 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 09/29/2008
Collation 125p
Abstract
Cultures of Chinese hamster ovary cells have been used to quantify specific locus mutation and to determine mutagenicity of chemicals (Hsie et al., 1981). The objective of this assay is to determine if the test substance can induce a mutation in standard cultures of mammalian cells either directly or after it has been activated by microsomal enzymes.