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RECORD NUMBER: 189 OF 287

OLS Field Name OLS Field Data
Main Title Mutagenic Activity of Carbitol in the Salmonella/microsome Assay with Attachments and Cover Sheet Dated 06/12/1989 (Sanitized).
CORP Author Du Pont de Nemours (E.I.) and Co., Newark, DE. Haskell Lab. for Toxicology and Industrial Medicine.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 2000
Report Number 86-890000829S
Stock Number OTS0520945
Additional Subjects Toxicology ; Health effects ; Diethylene Glycol Monoethyl Ether (111-90-0) ; Genotoxicity ; Gene Mutations ; Bacteria ; In Vitro ; Toxic substances ; Laboratory animals ; CAS No 111-90-0
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NTIS  OTS0520945 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 03/10/2010
Collation 8p
Abstract
The mutagenicity of Carbitol (diethylene glycol monoethyl ether) was evaluated in Salmonella tester strains TA98, TA100, TA1535, TA1537, and TA1538 (Ames Test), both in the presence and absence of added metabolic activation by Aroclor-induced rat liver S9 fraction. Based on the results of preliminary bacterial toxicity testing, the material was tested for mutagenicity at concentrations of 0, 3000, 6000, 9000, 12000, 15000, and 20000 ug/plate using the direct plate incorporation method. Carbitol did not cause a reproducible positive response in any of the bacterial tester strains, either in the presence or absence of added metabolic activation.