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RECORD NUMBER: 163 OF 287

OLS Field Name OLS Field Data
Main Title Letter from Gulf Oil Company to USEPA Regarding Information on the Mutation Assay and In Vitro Cell Transformation Testing Conducted at EG&G Mason Laboratories.
CORP Author Gulf Refining and Marketing Co., Houston, TX.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Publisher 9 Feb 1981
Year Published 1981
Report Number 8HEQ-0281-0385;
Stock Number OTS-0204916
Additional Subjects Mutations ; Cells(Biology) ; Toxicology ; In vitro analysis ; Rats ; Lymphomas ; Metabolism ; Exposure(Physiology) ; Bioassay ; Cultures(Biology) ; Plates ; Laboratory tests ; US EPA ; Gulf Oil Company
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  OTS-0204916 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 07/09/2008
Collation 332p
Abstract
This test involves the growth of mice cells in culture dishes in the presence of the material being tested (the experimental protocol used is a modification of that described by Clive, D. and Spector, J.F.S., Laboratory Procedure for Assessing Specific Locus Mutations at the TK Locus in Cultured L5178Y Mouse Lymphoma Cells. Mutation Research 31:17-29, (1975)). After the 'exposure' period, the cells are washed and placed in a growth medium which restricts the growth of 'normal' cells. Only mutant cells should grow in this medium. Control groups are used to detect the growth of any non-exposed cells in the medium.