Record Display for the EPA National Library Catalog
RECORD NUMBER: 156 OF 287
|OLS Field Name||OLS Field Data|
|Main Title||Letter from Allied Chemical Corporation to US EPA Submitting Testing Results of N-(4,6-dichloro-triazin-2-yl) Monosodium Salt.|
|CORP Author||Allied Chemical Corp., Buffalo, NY.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.|
|Additional Subjects||Toxicology ; Health effects ; Sandospace-R ; Acute toxicity ; Mammals ; Rabbits ; Dermal ; Primary dermal irritation ; Primary eye irritation ; Primary dermal sensitization ; Hamsters ; Genotoxicity ; Gene mutations ; Bacteria ; In vitro ; Chronic toxicity ; Cell transformation ; CAS No 4156-21-2 ; CAS No 5455-98-1|
N(2,3- epoxypropyl)phthalimide was assessed for acute toxicity. Summary information indicates the dermal LD50 for rabbits was 4.7 g/kg, it was slightly irritating to rabbit skin, moderately irritating to the rabbit eye, and did not induce hypersensitivity in the guinea pig. It was mutagenic in Chinese hamster ovary cells and active in the Ames test. The test material increased the frequency of viral transformation of Syrian hamster embryo cells, but did not produce increases in mutant frequency in the host-mediated assay. No further information was provided regarding experimental procedure or results.