Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Biological Calcification Normal and Pathological Processes in the Early Stages / [electronic resource] :
Author Bonucci, Ermanno.
Publisher Springer Berlin Heidelberg,
Year Published 2007
Call Number QP82-82.2
ISBN 9783540360131
Subjects Life sciences. ; Human physiology. ; Orthopedics. ; Biochemistry. ; Evolution (Biology). ; Morphology (Animals). ; Animal Physiology.
Internet Access
Description Access URL
Collation XXI, 592 p. 48 illus. online resource.
Due to license restrictions, this resource is available to EPA employees and authorized contractors only
Contents Notes
Historical Notes -- Methodology -- The Nature and Composition of the Inorganic Phase -- The Shape of Inorganic Particles -- The Size of Inorganic Particles -- Calcifying Matrices: Bone and Tendons -- Calcifying Matrices: Dentin and Cementum -- Calcifying Matrices: Cartilage -- Calcifying Matrices: Enamel -- Calcifying Matrices: Lower Vertebrates -- Calcifying Matrices: Invertebrates -- Calcifying Matrices: Non-skeletal Structures -- Calcifying Matrices: Pathological Calcifications -- Calcifying Matrices: Acquired or Experimental Diseases; Heritable Disorders; Genetically Modified Animals -- The Organic-inorganic Relationships in Calcifying Matrices -- Main Suggested Calcification Mechanisms: Cells -- Main Suggested Calcification Mechanisms: Extracellular Matrix -- Conclusions. This book follows a precursor volume devoted to biological calci?cation, - sued by the CRC Press, Boca Raton (Florida) in 1992. Several basic aspects of the calci?cation process were analyzed in it by outstanding authors who had unquestioned competence in their respective research areas. Its main aim was that of giving readers access to a series of papers which, even though they discussed divergent aspects of biological calci?cations drawn from the study of systems as different as vertebrate skeletons and mollusks, in vitro cultures and unicellular organisms, ectopic calci?cation and urinary stones, provided elements permitting a coherent approach to a comprehensive view of the calci?cation process in biological tissues. Now, almost 15 years after the publication of that book, a great variety of new data from a wide spectrum of biological organisms and systems has enriched our knowledge of the normal and pathological mechanisms which can lead to calci?cation. Even so, this whole process is still problematic: the new knowledge, concepts and ideas have often suggested that a de?nitive solution was close at hand, but the local mechanism through which the inorganic substance is laid down in organic matrices continues to be an elusive, largely enigmatic topic.