Record Display for the EPA National Library Catalog

RECORD NUMBER: 59 OF 1237

OLS Field Name OLS Field Data
Main Title Asbestos and gastro-intestinal cancer : cell culture studies /
Author Reiss, B. ; Weisburger, J. H. ; Williams, G. M.
Other Authors
Author Title of a Work
Weisburger, J. H.
Williams, G. M.
CORP Author American Health Foundation, Valhalla, NY. Naylor Dana Inst. for Disease Prevention.;Health Effects Research Lab., Cincinnati, OH.
Publisher Environmental Protection Agency, Office of Research and Development [Office of Health aand Ecological Effects], Health Effects Research Laboratory ; For sale by the National Technical Information Service,
Year Published 1979
Report Number EPA/600/1-79/023; EPA-R-803998-01
Stock Number PB-300 474
Subjects Asbestos--Toxicology. ; Cell culture. ; Intestines--Cancer. ; Stomach--Cancer.
Additional Subjects Asbestos ; Malignant neoplasms ; Gastrointestinal system ; Toxicology ; Silicate minerals ; Humans ; Intestines ; Liver ; Rats ; Concentration(Cimposition) ; Recommendations ; Exposure ; Air pollution ; In vitro analysis ; Embryos ; Mice ; Cancer ; Cell cltures ; Cytotoxicity ; Mutagenesis ; Toxic substances ; Environmental health ; Air polluion effects(Humans) ; Biological effects
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB-300 474 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 01/01/1988
Collation viii, 37 pages : illustrations ; 28 cm.
Abstract
Three forms of asbestos: amosite, crocidolite, and chrysotile, were assayed for their cytotoxicity and mutagenicity in cell clture. Using embjryonic human intestine derived and adult rat liver derived epitelial cells, the order of toxicity was chrysotile > amosite = crocidolite. Leaching in acid slightly increased the toxicity of amosite and crocidolite and greatly decreased the toxicity of chrysotile. High concentrations of all three asbestos forms were not mutagenic in cultures of rat liver-derived epithelial cells.
Notes
Grant no. R-803998-01. July 1979. Includes bibliographical references (pages 32-36). Microfiche.