||Mercury study report to Congress : volume 4. health effects of mercury and mercury compounds.
||Environmental Protection Agency, Research Triangle Park, NC. Office of Air Quality Planning and Standards.
|| Office of Air Quality Planning and Standards and Office of Research and Development, U.S. Environmental Protection Agency,
Mercury--Environmental aspects--United States. ;
Mercury--Toxicology--United States. ;
Factory and trade waste--Environmental aspects--United States. ;
Mercury wastes--Environmental aspects--United States.
Air pollution effects(Humans) ;
Dose-response relationships ;
Mercury compounds ;
Environmental exposure ;
Health effects ;
Public health ;
Risk assessment ;
Biological effects ;
Biological monitoring ;
Fetal development ;
Child development disorders ;
Maternal-fetal exchange ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
||328 pages : illustrations, maps ; 28 cm
This volume of the draft Mercury Study Report to Congress summarizes the available information on human health effects and animal data for hazard identification and dose-response assessment for three forms of mercury: elemental mercury, mercury chloride (inorganic mercury), and methylmercury (organic mercury). Effects are summarized by endpoint. The risk assessment evaluates carcinogenicity, mutagenicity, developmental toxicity and general systemic toxicity of these chemical species of mercury. Toxicokinetics (absorption, distribution, metabolism and excretion) are described for each of the three mercury species. PBPK models are described, but not applied in risk assessment. Reference doses are calculated for inorganic and methylmercury; a reference concentration for inhaled elemental mercury is provided. A quantitiative analysis of factors contributing to variability and uncertainty in the methylmercury RfD is provided in an appendix. Interations and sensitive populations are described.
Principal authors: Martha H. Keating [and others]. "December 1997." Includes bibliographical references. "EPA-452/R-97-007"--Cover, v. 5. Microfiche.