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RECORD NUMBER: 142 OF 281

OLS Field Name OLS Field Data
Main Title Evaluation of the Effects of Methanol during Early Pregnancy in the Rat.
Author Cummings, A. M. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. Developmental Toxicology Div.
Publisher c1993
Year Published 1993
Report Number EPA/600/J-93/377;
Stock Number PB93-231850
Additional Subjects Methanol ; Exposure ; Health ; Alternative fuels ; Pregnancy ; Rats ; Implantation ; Reprints ;
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB93-231850 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 11/22/1993
Collation 12p
Abstract
Recent attention to methanol (MeOH) as a potential alternative fuel prompted an evaluation of the chemical's effects during very early pregnancy. Rats were dosed by gavage during Days 1-8 of pregnancy at 0, 1.6, 2.4 or 3.2 g MeOH/kg/day. Groups of animals were killed on Days 9, 11 or 20 of pregnancy, and maternal, embryonic, or fetal parameters were assessed, depending on the stage of pregnancy. The decidual cell response (DCR) technique was also applied to rats treated with MeOH during pseudopregnancy. (Copyright (c) 1993 Elsevier Scientific Publishers Ireland Ltd.).