||Predicting Single-Species Toxicity in Natural Water Systems.
Connolly, J. P. ;
||Manhattan Coll., Bronx, NY. Dept. of Environmental Engineering and Science.;Environmental Research Lab., Gulf Breeze, FL.
Water pollution ;
Fresh water biology ;
Mathematical model ;
Water pollution effects(Animals) ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
A methodology is proposed to predict single-species toxicity in natural waters by using laboratory bioassay data which relate effect to a tissue concentration of toxicant or to injury accumulation. Such relationships should be independent of test conditions and therefore transferable from lab to field. A mathematical model of uptake and elimination of toxicants by fish is used to relate exposure concentration to tissue concentration and then to affect. Prediction of toxicity in a laboratory test in which the exposure concentration varies in time is presented as a first step in testing the methodology. Survival time under time-varying exposure is calculated and compared to observed data. The model predicted survival times that were consistent with the observed times. Whole-body residue is used as the estimate of dose.