Record Display for the EPA National Library Catalog

RECORD NUMBER: 17 OF 2109

OLS Field Name OLS Field Data
Main Title 14-day Subchronic Toxicity Study in Rats with 2-butenal.
CORP Author Borriston Labs., Inc., Temple Hills, MD.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1986
Report Number 878221649
Stock Number OTS0510394
Additional Subjects Toxicology ; Health effects ; 2-butenal (4170-30-3) ; Subchronic Toxicity ; Mammals ; Rats ; Oral ; Diet ; Toxic substances ; Laboratory animals ; CAS No 4170-30-3
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NTIS  OTS0510394 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 03/10/2010
Collation 28p
Abstract
In a subchronic toxicity study, male and female Sprague-Dawley rats (5/sex/group) were fed diets containing crotonaldehyde at dose nominal dose levels of 0, 22, 44, 88 or 175 mg/kg/day for 14 days. Actual mean dosages (male/female) for the above groups were: 0/0, 19/17, 36/36, 73/68, and 139/136 mg/kg/day, respectively. There were no statistically significant differences between treated and control animals in the following: mortality, clinical signs of toxicity, body weight, food consumption, efficiency of food utilization (change in body weight/weekly food consumption), and absolute or relative organ weights. There were no exposure-related gross lesions observed in any of the treated groups.