Record Display for the EPA National Library Catalog
RECORD NUMBER: 31 OF 98
|OLS Field Name||OLS Field Data|
|Main Title||Effect of Controlled Ozone Exposure on Human Lumphocyte Function.|
|Author||Peterson, Mirdza L. ; Smialowicz, Ralph ; Harder, Shirley ; Ketcham, Brock ; House, Dennis ;|
|CORP Author||Health Effects Research Lab., Research Triangle Park, NC.|
|Additional Subjects||Ozone ; Toxicology ; Lymphocytes ; Humans ; Exposure ; Blood cells ; Leukocytes ; Physiological effects ; Air pollution ; Reprints ; Cellular immunity ; Air pollution effects(Humans)|
The effects of ozone (03) on cell-mediated immunity were studied in 16 human subjects exposed to 1176 micrograms/cu.m. 03 (0.6 ppm) for 2 hr in an environmentally controlled exposure chamber. Venous blood smaples were taken before and immediately after controlled air and 03 exposures, as well as at 72 hr, 2 and 4 weeks, and at one random time at least 1 month after treatment. The relative frequency of T lymphocytes in blood and the in vitro blastogenic response of lymphocytes to phytohemagglutinin (PHA), concanavalin A (Con A), pokeweed mitogen (PWM), and Candida albicans were determined.