||Letter from (Confidential) to USEPA Submitting Local Lymph Node Assay Skin Sensitization Studies (7) for Chemical Substances and Mixtures (Confidential), with Attachments (6) and dated 08/30/2000 (Sanitized).
||; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Health effects ;
Skin sensitizations ;
Acute toxicity ;
Lymph nodes ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
A sample of (confidential) was assessed for its skin sensitisation potential using the mouse Lymph Node Assay. The assay determines the level of T lymphocyte proliferation in the lymph nodes draining the site of chemical application, by measuring the amount of radiolabelled thymidine incorporated into the dividing cells. The test substance was applied as 3%, 10% or 30% w/v preparations in acetone.