Record Display for the EPA National Library Catalog

RECORD NUMBER: 6 OF 16

OLS Field Name OLS Field Data
Main Title Initial Submission: Draft Pathology Report (Terminal Kill) in 13-Week Inhalation Toxicity Study in the Rat with 13-Week Treatment-Free Period, with Cover Letter dated 12/07/1999. (Sanitized).
CORP Author UOP, Inc., Des Plaines, IL.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1999
Report Number 8EHQ-1299-14613S
Stock Number OTS0559860
Additional Subjects Pathology ; Inhalation ; Toxicity ; Rats ; Lungs ; Lymph nodes ; Dosage ; Laboratory animals ; Histopathology ; Respiratory system ; Treatment ; Responses(Biology) ; Morbidity ; Mortality ; Terminal kill
Holdings
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NTIS  OTS0559860 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 04/28/2010
Collation 148p
Abstract
There were treatment-related changes in the lungs and bronchial lymph nodes of all treated group terminal kill animals. Microscopically, the findings in the lung were characterised by mild to moderate histiocytosis/proteinosis associated with perivascular cuffing/pneumonitis and increased peribronchial lymphoid response. Lymphoid hyperplasia and minor histiocyte foci were also found in the bronchial lymph nodes. A no observable effect level (NOEL) was not established.