Record Display for the EPA National Library Catalog

RECORD NUMBER: 46 OF 146

OLS Field Name OLS Field Data
Main Title EPA's Research to Improve Health Risk Assessments Program: Overview and Water-Related Research.
Author Vandenberg, J. J. ; Fowler, J. R. ; Zenick., H. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Publisher 1991
Year Published 1991
Report Number EPA/600/D-91/187;
Stock Number PB91-231068
Additional Subjects Risk assessment ; Potable water ; Water pollution effects(Humans) ; Water pollution standards ; Dose-response relationships ; Dose limits ; Occupational safety and health ; Public health ; Pollution laws ; US EPA ; Exposure ; Biological effects ; Probability theory ; Physiology ; Mathematical models ; Research to Improve Health Risk Assessments Program ; Pharmacokinetics
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB91-231068 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 11/26/1991
Collation 13p
Abstract
Federal law requires the Environmental Protection Agency (EPA) to assess drinking water risks and to set standards to insure a safe drinking water supply. Given limited data, risk assessors rely on high dose experimental data, results from occupational health studies, and other data sets (e.g., in vitro tests) to make predictions about health outcomes. A variety of assumptions and extrapolations must be used to estimate from the results of these studies the likelihood of adverse health effects associated with a lifetime of water consumption. In recognition that the uncertainties in risk assessment may result in economic burdens (i.e., from over regulation) or inadequate public safety (i.e., from under regulation), EPA has established the Research to Improve Health Risk Assessments (RIHRA) program to resolve some of the major health risk assessment issues. The paper presents an overview of the RIHRA program and several examples of health research applicable to drinking water issues.