Main Title |
A rapid method for estimating log P for organic chemicals / |
Author |
Veith, Gilman D., ;
Morris., Richard T.
|
Other Authors |
|
CORP Author |
Environmental Research Lab.-Duluth, Minn. ;Wisconsin Univ.-Superior. |
Publisher |
Environmental Protection Agency, Office of Research and Development, Environmental Research Laboratory, |
Year Published |
1978 |
Report Number |
EPA 600-3-78-049 |
Stock Number |
PB-284 386 |
OCLC Number |
04146579 |
ISBN |
pbk. |
Subjects |
Liquid chromatography ;
Logarithms
|
Additional Subjects |
Organic compounds ;
Chemical analysis ;
Chromatographic analysis ;
High temperature tests ;
Numerical solutions ;
Calibrating ;
Solutions ;
Laboratory equipment ;
Liquid chromatography ;
Partition coefficients ;
Procedures
|
Internet Access |
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
EJBD ARCHIVE |
EPA 600-3-78-049 |
|
Headquarters Library/Washington,DC |
11/29/2023 |
EJBD |
EPA 600-3-78-049 |
|
Headquarters Library/Washington,DC |
01/09/2020 |
EKBD |
EPA-600/3-78-049 |
|
Research Triangle Park Library/RTP, NC |
08/11/2000 |
EKCD |
EPA-600/3-78-049 |
|
CEMM/GEMMD Library/Gulf Breeze,FL |
06/26/2018 |
ELBD ARCHIVE |
EPA 600-3-78-049 |
Received from HQ |
AWBERC Library/Cincinnati,OH |
10/04/2023 |
DISPERSAL |
ELDD |
EPA-600/3-78-049 |
|
CCTE/GLTED Library/Duluth,MN |
05/04/2001 |
ERAD |
EPA 600/3-78-049 |
|
Region 9 Library/San Francisco,CA |
10/22/2012 |
ESAD |
EPA 600-3-78-049 |
|
Region 10 Library/Seattle,WA |
03/23/2010 |
NTIS |
PB-284 386 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
viii, 16 pages : illustrations ; 28 cm. |
Abstract |
A rapid, inexpensive technique based on reverse-phase high pressure liquid chromatography has been developed to estimate the n-octanol/water partition coefficient of organic chemicals. The system consists of a preparative Micro-Pak C-(R)10 reverse-phase column eluted with a 15 percent water/85 percent methanol solvent flowing at 2 ml/min at room temperature. The chemicals are detected in the eluant with a standard ultraviolet detector or a fraction collector system followed by appropriate analysis of the fractions to determine the retention time of the chemical. A linear calibration of the logarithm of retention time with the logarithm of the partition coefficient (Log P) is attained by using a mixture of benzene, bromobenzene, biphenyl, bibenzyl, pp'DDE, and 2,4,5,2',5' pentachlorobiphenyl as reference standards of known Log P. Chemicals with Log P of approximately 3 elute in less than 10 min whereas those with Log P greater than 5 elute after 20 min. |
Notes |
"EPA 600-3-78-049." "May 1978." Includes bibliographical references (page 15). |