Abstract |
In response to the need to improve scientific and regulatory decisions and to provide additional guidance for evaluating the acute toxicity of chemical exposures under the Federal Insecticide, Fungicide and Rodenticide Act and the Toxic Substances Control Act. The action builds upon a previous revision of the acute toxicity testing strategy to reduce the use of experimental animals while providin g adequate information about chemical safety. The Environmental Protection Agency is disseminating the notice to industry, governmental bodies, scientific societies, animal welfare groups and interested parties. The Agency's acute toxicity testing guidelines are being revised to reflect the positions articulated in the policy. |