Abstract |
With respect to the character of its effect, TiCl4 is an irritant. The toxicity of TiCl4 depended on atmospheric humidity. With an increase in humidity, the toxicity decreased. At an absolute humidity of 5 - 7 mm Hg, LD50 is approximately 0.1 mg/l, and at an absolute humidity of 10 - 17 mm Hg - 0.4 mg/l. A reduction in oxygen consumption, an increase in the summation capacity of the central nervous system, and death ensued with symptoms of edema and pulmonary hemorrhages in the poisoned animals. The animals that survived after a single inhalation dose were less sensitive to repeated exposure to this product a month after the first exposure. |