Record Display for the EPA National Library Catalog
RECORD NUMBER: 2875 OF 4452Main Title | Mutagenicity Evaluation of Down Corning X3-9058 in the Ames Bacterial Assay, with Cover Letter dated 04/20/1994. | |||||||||||
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CORP Author | Dow Corning Corp., Midland, MI.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. | |||||||||||
Year Published | 1994 | |||||||||||
Report Number | OTS-86940001341 | |||||||||||
Stock Number | OTS0558122 | |||||||||||
Additional Subjects | Toxicology ; Health effects ; Toxic substances ; Siloxanes ; Silicones ; DI-ME ; OH-TERM'd ; Laboratory animals ; Genotoxicity ; Gene mutations ; Bacteria ; In vitro ; CAS No 70131-62-9 ; CAS No 7631-86-9 | |||||||||||
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Collation | 15p | |||||||||||
Abstract | The test material was evaluated for genetic activity in a microbial assay (knes, et al., MUTATION RESEARCH, 31:347, 1975) with and without the addition of mammalian metabolic activation. Salmonella typhimurium Str. TA-1535, TA-1537, TA-1538, TA-98, and TA-100 were used as indicator organisms. The test material was introduced in the test system in sterile distilled water at concentrations ranging from 0.5 to 500 yg. A spot Plate Test against each strain was also conducted on diluted material at 1,000 pg final concentration. No evidence of genetic activity was observed. |